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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A16 All Species: 22.12
Human Site: T282 Identified Species: 32.44
UniProt: P16260 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16260 NP_689920.1 332 36224 T282 P E F E K C L T M R D T M K Y
Chimpanzee Pan troglodytes XP_001168284 332 36249 T282 P E F E K C L T M R D T M K Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546134 332 36141 T282 P E F E K C L T M W E T M K Y
Cat Felis silvestris
Mouse Mus musculus Q8C0K5 332 36201 T282 P E F E K C L T M R E T M K Y
Rat Rattus norvegicus P16261 322 35038 A275 R R R M Q L G A V L P E F E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520566 324 35638 T274 P D S E K C L T M L K T L K Y
Chicken Gallus gallus XP_421570 320 35184 T270 P D S E K C L T M V Q T L K Y
Frog Xenopus laevis Q5PQ27 327 36043 A279 G T M Q E I V A E E G F I R G
Zebra Danio Brachydanio rerio Q0P483 321 35318 T268 V T G H T Y S T V L G T M R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624199 316 35726 M268 S M L Q T I K M I Y K E N G I
Nematode Worm Caenorhab. elegans Q20799 588 66319 Q494 G Q F K Y I L Q N E G V T G F
Sea Urchin Strong. purpuratus XP_789697 271 30376 K224 N L K T V V E K H G F L G L Y
Poplar Tree Populus trichocarpa XP_002308549 340 37252 Q292 L S T I V R N Q G W K Q L F A
Maize Zea mays P29518 436 46609 L376 L H A I Y C I L K K E G A G G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172908 331 36237 R284 D G L N T I V R T Q G W K Q L
Baker's Yeast Sacchar. cerevisiae P38702 357 40807 K306 P K T M Y D H K F Q S I S E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 96 N.A. 92.7 88.8 N.A. 82.5 81 37 38.2 N.A. N.A. 50.2 20.2 39.7
Protein Similarity: 100 99.6 N.A. 98.1 N.A. 96.6 92.7 N.A. 87.9 86.7 54.2 53.9 N.A. N.A. 62 31.6 53.6
P-Site Identity: 100 100 N.A. 86.6 N.A. 93.3 0 N.A. 66.6 66.6 0 20 N.A. N.A. 0 13.3 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 20 N.A. 80 80 33.3 33.3 N.A. N.A. 13.3 33.3 6.6
Percent
Protein Identity: 34.4 21.7 N.A. 37.9 37.5 N.A.
Protein Similarity: 54.4 34.8 N.A. 53.6 55.1 N.A.
P-Site Identity: 0 6.6 N.A. 0 6.6 N.A.
P-Site Similarity: 6.6 26.6 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 13 0 0 0 0 7 0 7 % A
% Cys: 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 13 0 0 0 7 0 0 0 0 13 0 0 0 0 % D
% Glu: 0 25 0 38 7 0 7 0 7 13 19 13 0 13 7 % E
% Phe: 0 0 32 0 0 0 0 0 7 0 7 7 7 7 7 % F
% Gly: 13 7 7 0 0 0 7 0 7 7 25 7 7 19 13 % G
% His: 0 7 0 7 0 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 25 7 0 7 0 0 7 7 0 13 % I
% Lys: 0 7 7 7 38 0 7 13 7 7 19 0 7 38 7 % K
% Leu: 13 7 13 0 0 7 44 7 0 19 0 7 19 7 7 % L
% Met: 0 7 7 13 0 0 0 7 38 0 0 0 32 0 0 % M
% Asn: 7 0 0 7 0 0 7 0 7 0 0 0 7 0 0 % N
% Pro: 44 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 7 0 13 7 0 0 13 0 13 7 7 0 7 0 % Q
% Arg: 7 7 7 0 0 7 0 7 0 19 0 0 0 13 0 % R
% Ser: 7 7 13 0 0 0 7 0 0 0 7 0 7 0 0 % S
% Thr: 0 13 13 7 19 0 0 44 7 0 0 44 7 0 0 % T
% Val: 7 0 0 0 13 7 13 0 13 7 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 13 0 7 0 0 0 % W
% Tyr: 0 0 0 0 19 7 0 0 0 7 0 0 0 0 44 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _